EFFECTS OF TWO PHYTOTHERAPIC FORMULATIONS CONTAINING Glycine max (L.) MERR ON MALE RAT FERTILITY

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Clarissa Boemler Hollenbach
Carlos Eduardo Bortolini
Juliano Mattos Rodrigues
Lucas Hirtz
Fernanda Bastos de Mello
João Roberto Braga de Mello

Resumen

The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer’s recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1 , respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating, pregnancy and lactation. The total number of spermatozoa, their daily production sperm morphology, histopathology and weight of sexual organs were evaluated. The results showed the interference of the phytotherapic formulations A and B in the total number of spermatozoa and in the sperm morphology in a dose-dependent manner.

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1.
Boemler Hollenbach C, Bortolini CE, Mattos Rodrigues J, Hirtz L, Bastos de Mello F, Braga de Mello JR. EFFECTS OF TWO PHYTOTHERAPIC FORMULATIONS CONTAINING Glycine max (L.) MERR ON MALE RAT FERTILITY. Rev. Salud Anim. [Internet]. 22 de mayo de 2013 [citado 24 de noviembre de 2024];34(1):31. Disponible en: https://revistas.censa.edu.cu/index.php/RSA/article/view/70
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ARTÍCULOS ORIGINALES